Headquarters:
New York, New York, United States
Headline:
Managing Director & General Partner, SOSV
Followers:
1631
Connections:
1646
Company:
SOSV
Skills:
Mentoring, Startups, Clinical Development, Protein Expression, Protein Engineering, Monoclonal Antibodies, Business Development, Automation, Design of Experiments (DOE), Technological Innovation, Synthetic Biology, Project Mangement, Investment , Fundraising, Investments, Biochemistry, Biotechnology, Protein Chemistry, Molecular Biology, Drug Discovery, Start-ups, Cell Culture, Lifesciences, Cell Biology, Technology Transfer, Protein Purification, Life Sciences, R&D, Drug Development, Biopharmaceuticals, Pharmaceutical Industry, Purification, Project Management, Entrepreneurship, Consulting, Volunteering, Commercialization, Venture Capital, High Throughput Screening, Biophysics
Experience:
Title: Managing Director & General Partner at SOSV NY
Company: SOSV
Location: New York, United States
Start: Mar 2020
End: Present
Title: Royal Society Entrepreneur in Residence
Company: Imperial College London
Location: London, United Kingdom
Start: 2019
End: 2021
Title: Co Founder
Company: Bio-start
Location: London, United Kingdom
Start: Aug 2016
End: Jul 2018
Title: CEO
Company: SynbiCITE
Location: London, United Kingdom
Start: 2014
End: 2018
Title: Advisory Board Member
Company: London DNA Foundry
Location: London, United Kingdom
Start: 2014
End: 2018
Title: Co Founder
Company: Abpro
Location: Lexington, MA, USA
Start: 2008
End: 2013
Title: Director of Gene Expression
Company: Vertex Pharmaceuticals
Location: Cambridge, MA, USA
Start: 1990
End: 2007
Education:
School: University of Warwick
Degree: PhD
Field: Molecular Biology
Period:
School: University of Birmingham
Degree: MS
Field: Biotechnology
Period:
School: Bangor University
Degree: BS
Field: Biochemistry
Period:
Publications:
The Foundry: The DNA Synthesis and Construction Foundry @ Imperial College (Biochem. Soc. Trans. (2016) 44, 687–688; doi:10.1042/BST20160007 · Jun 15, 2016)
Designing experiments for high-throughput protein expression. (Methods in Molecular Biology: High-throughput Protein Expression and Purification, vol 498 (Doyle, S.A., ed.), Humana Press, pp19-29. · Jan 1, 2009)
E.coli and insect cell expression, automated purification and quantitative analysis. (Methods in Molecular Biology: Highthroughput Protein Expression and Purification, vol 498 (Doyle, S.A., ed.), Humana Press, pp143-156. · Jan 1, 2009)
Freedom of Expression (Freedom of Expression. Drug Discovery and Development, 11 (8): 31-33. · Jan 1, 2008)
Development of a protease production platform for structural-based drug design. (Current Protein and Peptide Science. 8: 439-445. · Jan 1, 2007)
Screening factors effecting a response in soluble protein expression: a formalized approach using design of experiments. (Analytical Biochemistry. 351: 122-127. · Jan 1, 2006)
Development of a high-throughput protein expression strategy. (BioProcessing. 3 (1): 41-45. · Jan 1, 2004)
Express Yourself (Drug Discovery Today. 9:475-477. · Jan 1, 2004)
Active-site residues of E.coli DNA gyrase required in coupling ATP hydrolysis to DNA supercoiling and amino acid substitutions (Antimicrobial Agents and Chemotherapy. 47: 1037- 1046 · Jan 1, 2003)
High-throughput protein expression for the post-genomic era. (Drug Discovery Today. 7:759-765. · Jan 1, 2002)
High-throughput screening for soluble recombinant expressed kinases in E.coli and insect cells. (Protein Expression and Purification. 36:40-47. · Jan 1, 2002)
Design and synthesis of amprenavir, a novel HIV protease inhibitor in Protease Inhibitors in AIDS Therapy (vol. 6 (Ogden and Flexner, eds.), Marcel Dekker, pp101-118. · Jan 1, 2000)
The structures of caspase-1, -3, -7 and -8 reveal the basis for substrate and inhibitor specificity. (Chemistry and Biology. 7; 423-432. · Jan 1, 2000)
My Bibliography ()
Awards:
Life Science Power 50: The scientists, entrepreneurs and investors driving New York’s biotech boom | City & State | Jan 2021
Royal Society's Industrial Fellows College | Royal Society | Apr 2019
Fellow of the Royal Society of Biology (FRSB) | Royal Society of Biology of the United Kingdom | Dec 2017
Country:
United States