Claire Brown Top-Executive
Authentic and accomplished business leader in both the US and Europe. 20+ years experience in operations, business creation & building, in-licensing and investing. Board member and executive with a passion for building the next generation of Life Science companies...
Headquarters:
United Kingdom
Followers:
2697
Title:
Partner
Company:
Oxford Science Enterprises
Company Linkedin:
https://www.linkedin.com/company/oxford-science-enterprises/
Current Job Duration:
5 yrs 10 mos
Country:
United Kingdom
License And Certifications:
Name: Investment Management Certificate
Authority: CFA Institute
Company ID: None
Date: 7/2017
URL: https://linkedin.com/company/162977
Name: Role of the Board
Authority: Institute of Directors (IoD)
Company ID: None
Date: 12/2018
URL: https://linkedin.com/company/21374
Work Experience:
Title: Partner
Company: Oxford Science Enterprises
Company URL: https://www.linkedin.com/company/oxford-science-enterprises/
Industry: None
Company Size: None
Location: Oxford, England, United Kingdom
Country: None
Employment Type: Full-time
Start At: 09-2020
Ends At: Present
Description: Investment Partner at OSE (evergreen fund, £1Bn under Management) responsible for new company creation and operational processes. Have had executive roles in parallel.
Title: Board of Directors
Company: Acionna Therapeutics
Company URL: None
Industry: None
Company Size: None
Location: None
Country: None
Employment Type: Part-time
Start At: 03-2025
Ends At: Present
Description: Acionna Therapeutics is a spin out from the Alzheimer's Research UK Oxford Drug Discovery Institute and the UK Dementia Research Institute at Cardiff University, developing novel therapeutics to target the neuroimmune cascade and improve synaptic function in Alzheimer’s disease and other CNS disorders
Title: Board of Directors
Company: Scripta Therapeutics
Company URL: https://www.linkedin.com/company/scripta-therapeutics/
Industry: Biotechnology
Company Size: 1-10
Location: None
Country: None
Employment Type: Part-time
Start At: 02-2025
Ends At: Present
Description: Neuro focused company
Title: Board Director
Company: Thelior Bio
Company URL: None
Industry: None
Company Size: None
Location: None
Country: None
Employment Type: None
Start At: 01-2025
Ends At: Present
Description: Stealth Newco focusing on IBD and epithelial Barrier repair
Title: Board Director
Company: T-Cypher Bio
Company URL: https://www.linkedin.com/company/68515106/
Industry: None
Company Size: None
Location: Oxford, England, United Kingdom
Country: None
Employment Type: Part-time
Start At: 09-2021
Ends At: Present
Description: T-Cypher Bio are developing next generation TCR-based Bispecifics that will transform therapy. Their proprietary platform allows unprecedented throughput, high-resolution profiling of the immune synapse enables them to map the intracellular target space.
Title: Board Director
Company: AlveoGene
Company URL: https://www.linkedin.com/company/98714323/
Industry: None
Company Size: None
Location: None
Country: None
Employment Type: Part-time
Start At: 07-2023
Ends At: Present
Description: Transforming rare respiratory disease using Inhaled Gene Therapy
Title: Board Director
Company: Orfonyx Bio
Company URL: https://www.linkedin.com/company/102267136/
Industry: None
Company Size: None
Location: None
Country: None
Employment Type: Part-time
Start At: 10-2022
Ends At: Present
Description: Orfonyx Bio are harnessing our unique insights and proprietary computational platform to develop an emerging class of genetic medicines that target regulatory elements in untranslated regions of genes
Title: Board Observer
Company: Nucleome Therapeutics
Company URL: https://www.linkedin.com/company/nucleome-therapeutics/
Industry: Biotechnology
Company Size: 11-50
Location: None
Country: None
Employment Type: None
Start At: 03-2023
Ends At: Present
Description: None
Title: Board Observer
Company: OMass Therapeutics
Company URL: https://www.linkedin.com/company/omass-therapeutics/
Industry: Biotechnology
Company Size: 11-50
Location: None
Country: None
Employment Type: Part-time
Start At: 11-2021
Ends At: 06-2024
Description: None
Title: Board Director
Company: Dark Blue Therapeutics
Company URL: https://www.linkedin.com/company/dark-blue-tx/
Industry: Biotechnology
Company Size: 1-10
Location: Oxford, England, United Kingdom
Country: None
Employment Type: None
Start At: 10-2020
Ends At: 04-2023
Description: None
Title: Board Director
Company: Alethiomics
Company URL: https://www.linkedin.com/company/76644628/
Industry: None
Company Size: None
Location: None
Country: None
Employment Type: Part-time
Start At: 08-2022
Ends At: 03-2023
Description: None
Title: Board Of Directors
Company: Kinomica Limited
Company URL: https://www.linkedin.com/company/kinomica/
Industry: Biotechnology
Company Size: 11-50
Location: London and Manchester, UK
Country: None
Employment Type: None
Start At: 05-2019
Ends At: 09-2021
Description: Kinomica are a precision medicine biotech focusing their phosphoproteomics platform for optimising patient stratification
Title: Head of Investment
Company: Pioneer Group
Company URL: https://www.linkedin.com/company/pioneergrp/
Industry: Commercial Real Estate
Company Size: 11-50
Location: Alderley Park
Country: None
Employment Type: Part-time
Start At: 04-2015
Ends At: 05-2021
Description: Led the investment activity Pioneer Group managing the APV Fund together with off balance sheet investments, shareholder relationships and portfolio success. Led and completed >20 diverse investments with a focus on Therapeutic platforms. Board responsibility for investee companies. 3x exits, 1x IPO, 2x launched products and 1x CTA
Title: Board of Directors
Company: NanoSyrinx
Company URL: https://www.linkedin.com/company/37526604/
Industry: None
Company Size: None
Location: Warwick, England, United Kingdom
Country: None
Employment Type: Part-time
Start At: 04-2020
Ends At: 09-2020
Description: NanoSyrinx are pioneering a novel technology platform for intracellular targeting. Applications being pursued include a novel therapeutic modality and cell and gene therapy.
Title: Board Of Directors
Company: Rinri Therapeutics Ltd.
Company URL: https://www.linkedin.com/company/rinri-therapeutics/
Industry: Biotechnology
Company Size: 11-50
Location: Sheffield, UK
Country: None
Employment Type: None
Start At: 03-2019
Ends At: 09-2020
Description: Rinri Therapeutics, a biotechnology company developing a novel cell-based therapy to restore hearing loss
Title: Director, Strategy, Business Development and Investment
Company: AstraZeneca
Company URL: https://www.linkedin.com/company/astrazeneca/
Industry: Pharmaceuticals
Company Size: 10001+
Location: UK
Country: None
Employment Type: Full-time
Start At: 11-2007
Ends At: 03-2015
Description: • Identified & supported investments for $400m Corporate Fund; successfully completed investment into G1 therapeutics ($12.5M), now Nasdaq listed
• Search and evaluation lead for clinical stage in-licensing opportunities in orphan, ‘white space’ and mainstream areas engineering projects through probability of success, financials & business case proposals. Projects included TYMLOS for Osteoporosis, Lokelma for CKD.
• Delivered 13 deals to full evaluation, 5 to term sheet status in 12 months (2 acquired /achieved IPO)
• Identified opportunistic areas for growth and licensing for AZ (osteoporosis, acute critical care, orphan disease, chronic kidney disease, incontinence, narcolepsy etc).
• Management of AZs corporate alliance with Galderma (securing 3 x Ph2a starts in <3yrs).
• Focused on repositioning parked /back up assets to leverage additional value and led the acute critical care (ACC) franchise.
• Structured, negotiated and managed >20 global alliances securing pivotal preclinical proof of concept data
• As project lead, progressed several assets to development decision (including intravenous PARP inhibitor for Acute MI/ALI etc)
Title: Principal Scientist, Pharmacology & Toxicology
Company: Sanofi Genzyme
Company URL: https://www.linkedin.com/company/sanofi/
Industry: Pharmaceuticals
Company Size: 10001+
Location: USA
Country: None
Employment Type: None
Start At: 01-2004
Ends At: 01-2007
Description: • Project lead successfully progressing towards, and supporting assets whilst in, the clinic
o Provided efficacy, safety and regulatory support (incl. GLP compliance).
o Key achievements include 1) Optimization delivery of Fabrazyme 2) Developed and executed a Tox strategy to allow the relinquishment of Olipudase alfa from clinical hold 3) Supported development of 2nd generation CartiCel 4) Progression and development of skeletal myoblasts for cardiac repair
In-licensing (Cell Tx, drug device combos, rhproteins, Artificial kidney etc)
Secretary/ Board Pulmonary focused Corporate Research Group (with GSK, J&J)
Title: Pharmacology Dept, Principal Scientist
Company: UCB Research Inc
Company URL: https://www.linkedin.com/company/ucb-pharma/
Industry: Pharmaceuticals
Company Size: 5001-10000
Location: None
Country: None
Employment Type: None
Start At: 01-2000
Ends At: 01-2004
Description: •Pioneered antitussive strategy at UCB and delivered clinical candidates. Scientist of the Year (2004).
•Group & Global project leader (CNS, allergy, respiratory). Leadership of chemistry, biology and DMPK teams (project conception through candidate selection) in addition to discovery efforts (COPD, cough, allergy, asthma and inflammation)
•Validated pivotal disease models allowing smooth and rapid transition from target validation to clinical candidate selection
Education:
School: University of Glasgow
Degree: BSc (Hons)
Field: Physiology
Period:
School: Glasgow Caledonian University
Degree: Ph.D
Field: Pharmacology
Period:
School: Loughborough University
Degree: MBA
Field: Business Administration and Management
Period:
School: CFA Institute
Degree: Investment Management Certification
Field:
Period: 2016 - 2016
Headline:
Life Science Executive, Investor and Board member
Connections:
2452
Company Website:
https://www.oxfordscienceenterprises.com, https://scriptatherapeutics.com, https://tcypherbio.com/, https://www.alveogene.com
Skills:
Drug Development, Life Sciences, Biotechnology, Drug Discovery, Pharmacology, R&D
Experience:
Title: Partner
Company: Oxford Science Enterprises
Location: Oxford, England, United Kingdom
Start: Sep 2020
End: Present
Title: Board of Directors
Company: Acionna Therapeutics
Location:
Start: Mar 2025
End: Present
Title: Board of Directors
Company: Scripta Therapeutics
Location:
Start: Feb 2025
End: Present
Title: Board Director
Company: Thelior Bio
Location:
Start: Jan 2025
End: Present
Title: Board Director
Company: T-Cypher Bio
Location: Oxford, England, United Kingdom
Start: Sep 2021
End: Present
Title: Board Director
Company: AlveoGene
Location:
Start: Jul 2023
End: Present
Title: Board Director
Company: Orfonyx Bio
Location:
Start: Oct 2022
End: Present
Title: Board Observer
Company: Nucleome Therapeutics
Location:
Start: Mar 2023
End: Present
Title: Board Observer
Company: OMass Therapeutics
Location:
Start: Nov 2021
End: Jun 2024
Title: Board Director
Company: Dark Blue Therapeutics
Location: Oxford, England, United Kingdom
Start: Oct 2020
End: Apr 2023
Title: Board Director
Company: Alethiomics
Location:
Start: Aug 2022
End: Mar 2023
Title: Board Of Directors
Company: Kinomica Limited
Location: London and Manchester, UK
Start: May 2019
End: Sep 2021
Title: Head of Investment
Company: Pioneer Group
Location: Alderley Park
Start: Apr 2015
End: May 2021
Title: Board of Directors
Company: NanoSyrinx
Location: Warwick, England, United Kingdom
Start: Apr 2020
End: Sep 2020
Title: Board Of Directors
Company: Rinri Therapeutics Ltd.
Location: Sheffield, UK
Start: Mar 2019
End: Sep 2020
Title: Director, Strategy, Business Development and Investment
Company: AstraZeneca
Location: UK
Start: Nov 2007
End: Mar 2015
Title: Principal Scientist, Pharmacology & Toxicology
Company: Sanofi Genzyme
Location: USA
Start: Jan 2004
End: Jan 2007
Title: Pharmacology Dept, Principal Scientist
Company: UCB Research Inc
Location:
Start: Jan 2000
End: Jan 2004