Betsy Barnes

Dr. Barnes’ laboratory studies a family of transcription factors – interferon (IFN) regulatory factors (IRFs) – that regulate immune cell signaling and the cellular response to extracellular stressors. She was the first to clone the family member IRF5 and show that it is an integral regulator of type I IFN gene expression. Later studies demonstrated its significant role(s) in mediating Toll-like r...