1.

Neurimmune Holding 2006

2.

Nomura Holdings

3.

Novartis 1996-03-22

4.

Novartis Venture Fund 1996-01-01

5.

Novo Holdings 1999-01-01

6.

Odey Asset Management 1991-01-01

7.

Old Mutual Wealth Life & Pension 2001

8.

Omega Funds 2004-01-01

9.

OncoEthix 2007

10.

Palmarium Undisclosed

11.

Paracelsus Clinic 1961

12.

PartnerRe

13.

Photoderma 01.05.2003

14.

PIQUR Therapeutics 2011

15.

PMV Tina Fund 2012

16.

PPF Group 1991

17.

Pregnolia 01-01-2016

18.

Preon Capital Partners Jan 1, 2014

19.

Prexton Therapeutics 2012

20.

Prof. Anna Jazwinska Müller Research Group, University of Fribourg Undisclosed

21.

Prof. Christoph Handschin Research Group, University of Basel Undisclosed

22.

Prof. Markus Rüegg Research Group, University of Basel Undisclosed

23.

Prof. Michael N. Hall Research Group, University of Basel Undisclosed

24.

Prof. Thomas Flatt Research Group, University of Fribourg Undisclosed

25.

Quest Capital Management 1987