{
  "FullStudy":{
    "Rank":217618,
    "Study":{
      "ProtocolSection":{
        "IdentificationModule":{
          "NCTId":"NCT01519050",
          "OrgStudyIdInfo":{
            "OrgStudyId":"KEK ZH 2011- 0274"
          },
          "Organization":{
            "OrgFullName":"University of Zurich",
            "OrgClass":"OTHER"
          },
          "BriefTitle":"Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral Regurgitation"
        },
        "StatusModule":{
          "StatusVerifiedDate":"January 2012",
          "OverallStatus":"Unknown status",
          "LastKnownStatus":"Recruiting",
          "ExpandedAccessInfo":{
            "HasExpandedAccess":"No"
          },
          "StartDateStruct":{
            "StartDate":"November 2011"
          },
          "PrimaryCompletionDateStruct":{
            "PrimaryCompletionDate":"May 2014",
            "PrimaryCompletionDateType":"Anticipated"
          },
          "CompletionDateStruct":{
            "CompletionDate":"May 2014",
            "CompletionDateType":"Anticipated"
          },
          "StudyFirstSubmitDate":"January 23, 2012",
          "StudyFirstSubmitQCDate":"January 25, 2012",
          "StudyFirstPostDateStruct":{
            "StudyFirstPostDate":"January 26, 2012",
            "StudyFirstPostDateType":"Estimate"
          },
          "LastUpdateSubmitDate":"January 25, 2012",
          "LastUpdatePostDateStruct":{
            "LastUpdatePostDate":"January 26, 2012",
            "LastUpdatePostDateType":"Estimate"
          }
        },
        "SponsorCollaboratorsModule":{
          "ResponsibleParty":{
            "ResponsiblePartyType":"Sponsor"
          },
          "LeadSponsor":{
            "LeadSponsorName":"University of Zurich",
            "LeadSponsorClass":"OTHER"
          },
          "CollaboratorList":{
            "Collaborator":[
              {
                "CollaboratorName":"Edwards Lifesciences",
                "CollaboratorClass":"INDUSTRY"
              }
            ]
          }
        },
        "OversightModule":{},
        "DescriptionModule":{
          "BriefSummary":"The aim of the study is to investigate whether a predictive score (combination of several validated predictors) better predicts postoperative left ventricular function than any single predictor in patients undergoing mitral valve repair for degenerative mitral regurgitation.\n\nA single center, prospective cohort study"
        },
        "ConditionsModule":{
          "ConditionList":{
            "Condition":[
              "Severe Degenerative Mitral Regurgitation"
            ]
          }
        },
        "DesignModule":{
          "StudyType":"Observational",
          "DesignInfo":{
            "DesignObservationalModelList":{
              "DesignObservationalModel":[
                "Cohort"
              ]
            },
            "DesignTimePerspectiveList":{
              "DesignTimePerspective":[
                "Prospective"
              ]
            }
          },
          "EnrollmentInfo":{
            "EnrollmentCount":"100",
            "EnrollmentType":"Anticipated"
          }
        },
        "ArmsInterventionsModule":{
          "InterventionList":{
            "Intervention":[
              {
                "InterventionType":"Behavioral",
                "InterventionName":"mitral valve repair",
                "InterventionDescription":"Mitral valve repair in patients with degenerative mitral regurgitation"
              }
            ]
          }
        },
        "EligibilityModule":{
          "EligibilityCriteria":"Inclusion criteria:\n\nAge 18- 85 years\nPatients with severe degenerative mitral regurgitation undergoing mitral valve repair at our institution\n\nExclusion criteria:\n\nFunctional or ischemic mitral regurgitation\nPresence of relevant (symptomatic) Coronary Artery Disease\nInability of exercising on semi supine bicycle",
          "HealthyVolunteers":"No",
          "Gender":"All",
          "MinimumAge":"18 Years",
          "MaximumAge":"85 Years",
          "StdAgeList":{
            "StdAge":[
              "Adult",
              "Older Adult"
            ]
          },
          "StudyPopulation":"100 patients with mitral valve proplapse ondergoing mitral valve repair for severe mitral regurgitation",
          "SamplingMethod":"Probability Sample"
        },
        "ContactsLocationsModule":{
          "CentralContactList":{
            "CentralContact":[
              {
                "CentralContactName":"Ines Bühler, Study Coordinator",
                "CentralContactRole":"Contact",
                "CentralContactPhone":"+41 (0)44 255 11 11",
                "CentralContactEMail":"ines.buehler@usz.ch"
              },{
                "CentralContactName":"Patric Biaggi, MD",
                "CentralContactRole":"Contact",
                "CentralContactEMail":"patric.biaggi@usz.ch"
              }
            ]
          },
          "OverallOfficialList":{
            "OverallOfficial":[
              {
                "OverallOfficialName":"Patric Biaggi, MD, Senior physican",
                "OverallOfficialAffiliation":"University Hospital Zurich, Division of Cardiology",
                "OverallOfficialRole":"Principal Investigator"
              }
            ]
          },
          "LocationList":{
            "Location":[
              {
                "LocationFacility":"University Hospital Zurich, Division of Cardiology",
                "LocationStatus":"Recruiting",
                "LocationCity":"Zurich",
                "LocationState":"ZH",
                "LocationZip":"8091",
                "LocationCountry":"Switzerland"
              }
            ]
          }
        }
      },
      "DerivedSection":{
        "MiscInfoModule":{
          "VersionHolder":"April 22, 2020"
        },
        "ConditionBrowseModule":{
          "ConditionMeshList":{
            "ConditionMesh":[
              {
                "ConditionMeshId":"D000008944",
                "ConditionMeshTerm":"Mitral Valve Insufficiency"
              }
            ]
          },
          "ConditionAncestorList":{
            "ConditionAncestor":[
              {
                "ConditionAncestorId":"D000006349",
                "ConditionAncestorTerm":"Heart Valve Diseases"
              },{
                "ConditionAncestorId":"D000006331",
                "ConditionAncestorTerm":"Heart Diseases"
              },{
                "ConditionAncestorId":"D000002318",
                "ConditionAncestorTerm":"Cardiovascular Diseases"
              }
            ]
          },
          "ConditionBrowseLeafList":{
            "ConditionBrowseLeaf":[
              {
                "ConditionBrowseLeafId":"M10493",
                "ConditionBrowseLeafName":"Mitral Valve Insufficiency",
                "ConditionBrowseLeafAsFound":"Mitral Regurgitation",
                "ConditionBrowseLeafRelevance":"high"
              },{
                "ConditionBrowseLeafId":"M8020",
                "ConditionBrowseLeafName":"Heart Valve Diseases",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"M8002",
                "ConditionBrowseLeafName":"Heart Diseases",
                "ConditionBrowseLeafRelevance":"low"
              }
            ]
          },
          "ConditionBrowseBranchList":{
            "ConditionBrowseBranch":[
              {
                "ConditionBrowseBranchAbbrev":"BC14",
                "ConditionBrowseBranchName":"Heart and Blood Diseases"
              },{
                "ConditionBrowseBranchAbbrev":"All",
                "ConditionBrowseBranchName":"All Conditions"
              }
            ]
          }
        }
      }
    }
  }
}