{
  "FullStudy":{
    "Rank":218273,
    "Study":{
      "ProtocolSection":{
        "IdentificationModule":{
          "NCTId":"NCT01510470",
          "OrgStudyIdInfo":{
            "OrgStudyId":"D2011028"
          },
          "Organization":{
            "OrgFullName":"Hong Kong Brånemark Osseointegration Center",
            "OrgClass":"OTHER"
          },
          "BriefTitle":"Clinical and Radiological Outcomes Study on Astra Tech Osseospeed Tx Profile Implant",
          "OfficialTitle":"Clinical and Radiological Outcomes Study on Astra Tech Osseospeed Tx Profile Implant"
        },
        "StatusModule":{
          "StatusVerifiedDate":"January 2012",
          "OverallStatus":"Unknown status",
          "LastKnownStatus":"Enrolling by invitation",
          "ExpandedAccessInfo":{
            "HasExpandedAccess":"No"
          },
          "StartDateStruct":{
            "StartDate":"January 2012"
          },
          "PrimaryCompletionDateStruct":{
            "PrimaryCompletionDate":"December 2013",
            "PrimaryCompletionDateType":"Anticipated"
          },
          "CompletionDateStruct":{
            "CompletionDate":"December 2013",
            "CompletionDateType":"Anticipated"
          },
          "StudyFirstSubmitDate":"January 11, 2012",
          "StudyFirstSubmitQCDate":"January 13, 2012",
          "StudyFirstPostDateStruct":{
            "StudyFirstPostDate":"January 16, 2012",
            "StudyFirstPostDateType":"Estimate"
          },
          "LastUpdateSubmitDate":"January 13, 2012",
          "LastUpdatePostDateStruct":{
            "LastUpdatePostDate":"January 16, 2012",
            "LastUpdatePostDateType":"Estimate"
          }
        },
        "SponsorCollaboratorsModule":{
          "ResponsibleParty":{
            "ResponsiblePartyType":"Principal Investigator",
            "ResponsiblePartyInvestigatorFullName":"Dr. Philip Lee KM",
            "ResponsiblePartyInvestigatorTitle":"Director, Hong Kong Brånemark Osseointegration Center",
            "ResponsiblePartyInvestigatorAffiliation":"Hong Kong Brånemark Osseointegration Center"
          },
          "LeadSponsor":{
            "LeadSponsorName":"Hong Kong Brånemark Osseointegration Center",
            "LeadSponsorClass":"OTHER"
          },
          "CollaboratorList":{
            "Collaborator":[
              {
                "CollaboratorName":"Dentsply Sirona Implants",
                "CollaboratorClass":"INDUSTRY"
              }
            ]
          }
        },
        "OversightModule":{
          "OversightHasDMC":"Yes"
        },
        "DescriptionModule":{
          "BriefSummary":"The Astra Tech Osseospeed Profile Implant design when placed in the healed extraction site maintains the marginal bone level"
        },
        "ConditionsModule":{
          "ConditionList":{
            "Condition":[
              "Malocclusion; Displaced or Missing Teeth"
            ]
          },
          "KeywordList":{
            "Keyword":[
              "AstraTech Osseospeed Profile Implant",
              "Marginal bone level",
              "soft tissue",
              "soft tissue responds"
            ]
          }
        },
        "DesignModule":{
          "StudyType":"Observational",
          "DesignInfo":{
            "DesignObservationalModelList":{
              "DesignObservationalModel":[
                "Case-Only"
              ]
            },
            "DesignTimePerspectiveList":{
              "DesignTimePerspective":[
                "Prospective"
              ]
            }
          },
          "EnrollmentInfo":{
            "EnrollmentCount":"15",
            "EnrollmentType":"Anticipated"
          }
        },
        "EligibilityModule":{
          "EligibilityCriteria":"Inclusion Criteria:\n\nPatients with single missing maxillary or mandibular premolar or molar\nThe edentulous sites should be healed sites\nThe opposing tooth will be a natural dentition\n\nExclusion Criteria:\n\ngeneral contraindications to dental implant surgery\nPatient with irradiation in the head and neck region\nImmuno-suppressed or immuno-compromised patients\nPatients who took or are taking amino-bisphosphonates\nPatients with poor oral hygiene and motivation\nPatients with untreated periodontitis\nUncontrolled diabetes\nPregnancy or lactation\nAddiction to alcohol or other drugs\npatients with psychiatric problems\nLack of occluding dentition/prosthesis\nRestricted mouth opening (less than 3.5cm inter-arch anteriorly)\nPatients with an acute or chronic infection/inflammation in the area intended for implant placement\nPatients unable to commit 5 years follow up\nPatients referred for implant placement only",
          "HealthyVolunteers":"Accepts Healthy Volunteers",
          "Gender":"All",
          "MinimumAge":"20 Years",
          "StdAgeList":{
            "StdAge":[
              "Adult",
              "Older Adult"
            ]
          },
          "StudyPopulation":"Patients with single missing maxillary or mandibular premolar or molar",
          "SamplingMethod":"Non-Probability Sample"
        },
        "ContactsLocationsModule":{
          "LocationList":{
            "Location":[
              {
                "LocationFacility":"Hong Kong Brånemark Osseointegration Centre",
                "LocationCity":"Hong Kong SAR",
                "LocationCountry":"China"
              }
            ]
          }
        }
      },
      "DerivedSection":{
        "MiscInfoModule":{
          "VersionHolder":"April 22, 2020"
        },
        "ConditionBrowseModule":{
          "ConditionMeshList":{
            "ConditionMesh":[
              {
                "ConditionMeshId":"D000008310",
                "ConditionMeshTerm":"Malocclusion"
              },{
                "ConditionMeshId":"D000016388",
                "ConditionMeshTerm":"Tooth Loss"
              },{
                "ConditionMeshId":"D000000848",
                "ConditionMeshTerm":"Anodontia"
              }
            ]
          },
          "ConditionAncestorList":{
            "ConditionAncestor":[
              {
                "ConditionAncestorId":"D000014076",
                "ConditionAncestorTerm":"Tooth Diseases"
              },{
                "ConditionAncestorId":"D000009057",
                "ConditionAncestorTerm":"Stomatognathic Diseases"
              },{
                "ConditionAncestorId":"D000010510",
                "ConditionAncestorTerm":"Periodontal Diseases"
              },{
                "ConditionAncestorId":"D000009059",
                "ConditionAncestorTerm":"Mouth Diseases"
              },{
                "ConditionAncestorId":"D000014071",
                "ConditionAncestorTerm":"Tooth Abnormalities"
              },{
                "ConditionAncestorId":"D000018640",
                "ConditionAncestorTerm":"Stomatognathic System Abnormalities"
              },{
                "ConditionAncestorId":"D000000013",
                "ConditionAncestorTerm":"Congenital Abnormalities"
              }
            ]
          },
          "ConditionBrowseLeafList":{
            "ConditionBrowseLeaf":[
              {
                "ConditionBrowseLeafId":"M9884",
                "ConditionBrowseLeafName":"Malocclusion",
                "ConditionBrowseLeafAsFound":"Malocclusion",
                "ConditionBrowseLeafRelevance":"high"
              },{
                "ConditionBrowseLeafId":"M17406",
                "ConditionBrowseLeafName":"Tooth Loss",
                "ConditionBrowseLeafAsFound":"Missing Teeth",
                "ConditionBrowseLeafRelevance":"high"
              },{
                "ConditionBrowseLeafId":"M2755",
                "ConditionBrowseLeafName":"Anodontia",
                "ConditionBrowseLeafAsFound":"Missing Teeth",
                "ConditionBrowseLeafRelevance":"high"
              },{
                "ConditionBrowseLeafId":"M15414",
                "ConditionBrowseLeafName":"Tooth Diseases",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"M10600",
                "ConditionBrowseLeafName":"Stomatognathic Diseases",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"M12002",
                "ConditionBrowseLeafName":"Periodontal Diseases",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"M10602",
                "ConditionBrowseLeafName":"Mouth Diseases",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"M15409",
                "ConditionBrowseLeafName":"Tooth Abnormalities",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"M12",
                "ConditionBrowseLeafName":"Congenital Abnormalities",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"M19311",
                "ConditionBrowseLeafName":"Stomatognathic System Abnormalities",
                "ConditionBrowseLeafRelevance":"low"
              },{
                "ConditionBrowseLeafId":"T416",
                "ConditionBrowseLeafName":"Anodontia",
                "ConditionBrowseLeafAsFound":"Missing Teeth",
                "ConditionBrowseLeafRelevance":"high"
              }
            ]
          },
          "ConditionBrowseBranchList":{
            "ConditionBrowseBranch":[
              {
                "ConditionBrowseBranchAbbrev":"BC07",
                "ConditionBrowseBranchName":"Mouth and Tooth Diseases"
              },{
                "ConditionBrowseBranchAbbrev":"All",
                "ConditionBrowseBranchName":"All Conditions"
              },{
                "ConditionBrowseBranchAbbrev":"BC16",
                "ConditionBrowseBranchName":"Diseases and Abnormalities at or Before Birth"
              },{
                "ConditionBrowseBranchAbbrev":"Rare",
                "ConditionBrowseBranchName":"Rare Diseases"
              }
            ]
          }
        }
      }
    }
  }
}